Deflazacort 6 mg / 5 ml Suspension (30 ml) Use, Indication, Side Effects, Dosage, Mechanism of Action, Price, Contra-Indications, Drug Interactions....

BERICORT Suspension

Deflazacort 6 mg / 5 ml Suspension (30 ml)

Deflazacort is a corticosteroid used to treat various inflammatory and autoimmune conditions. It is often prescribed when other corticosteroids, like prednisone, are not well tolerated.

Uses & Indications of Bericort Suspension:

Deflazacort is used to treat conditions such as:

• Inflammatory and autoimmune disorders: Rheumatoid arthritis, lupus, ulcerative colitis, Crohn’s disease
• Allergic reactions: Severe allergies, asthma
• Neurological diseases: Duchenne muscular dystrophy (DMD)
• Skin conditions: Eczema, psoriasis
• Organ transplantation: To prevent organ rejection
• Blood disorders: Certain types of anemia and platelet disorders

Mechanism of Action of Deflazacort Suspension:

Deflazacort is a glucocorticoid that works by:

• Suppressing the immune system
• Reducing inflammation by inhibiting the release of inflammatory substances
• Preventing tissue damage from overactive immune responses

It gets converted into an active metabolite in the liver, which has similar effects to prednisone but with potentially fewer side effects on bone health and glucose metabolism.

Dosage of Bericort Suspension:

Dosage depends on the condition being treated and the patient’s weight/response to therapy.

General Dosage Guidelines:

• Adults: 6–90 mg per day, depending on the condition
• Duchenne Muscular Dystrophy: 0.9 mg/kg per day
• Children: Doses are weight-based and should be prescribed by a doctor
• Elderly: Lower doses may be recommended due to potential side effects

It is best taken with food to reduce stomach irritation.

Side Effects of Bericort Suspension:

Common side effects:

• Weight gain
• Increased appetite
• Insomnia
• Mood changes (anxiety, irritability)
• Indigestion
• Increased blood sugar levels

Serious side effects (long-term use or high doses):

• Osteoporosis (bone loss)
• Hypertension (high blood pressure)
• Cushing’s syndrome (moon face, fat redistribution)
• Glaucoma or cataracts
• Infections due to weakened immunity
• Growth suppression in children

Contraindications of Deflazacort Suspension:

Deflazacort should not be used in:

• Active infections (e.g., tuberculosis, fungal infections)
• Uncontrolled diabetes
• Osteoporosis
• Peptic ulcers
• Severe psychiatric conditions (e.g., psychosis)

Caution is needed in pregnant and breastfeeding women only use if absolutely necessary.

Drug Interactions of Bericort Suspension:

Deflazacort interacts with:

• NSAIDs (e.g., ibuprofen, aspirin): Increased risk of stomach ulcers
• Antidiabetic medications: May increase blood sugar levels
• Antihypertensives: Can raise blood pressure
• Live vaccines: Can reduce vaccine effectiveness and increase infection risk
• Antifungals (e.g., ketoconazole): May increase steroid levels in the blood
• Anticonvulsants (e.g., phenytoin, carbamazepine): May decrease effectiveness of Deflazacort

How Deflazacort Suspension works:

Deflazacort is a corticosteroid drug. It increases the level of glucocorticoid in the body and works by decreasing the formation of substances that cause inflammation and suppresses immunity to stops self damage to body by immune system (auto-immune reactions occurring in organ transplants or cancer).

For Use of Registered Medical Practitioner or A Hospital Only

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