Aceclofenac 100 mg, Paracetamol 325 mg, Serratiopeptidase (EC) 15 mg Tablet Use, Indication, Side Effects, Dosage, Mechanism of Action, Price, Contra-Indications, Drug Interactions...

Hetrofen Sp Tablet

Aceclofenac 100 Mg, Paracetamol 325 Mg,Serratiopeptidase (Ec)15 Mg Tablet 

Hetrofen Sp Tablet Is Orally Administered For The Relief Of Pain And Inflammation In Osteoarthritis, Rheumatoid Arthritis And Ankylosing Spondylitis.

Hetrofen SP Tablet is a combination medication containing:

• Aceclofenac (100 mg) – a Non Steroidal Anti Inflammatory Drug (NSAID)
• Paracetamol (500 mg) – an Analgesic and Antipyretic
• Serratiopeptidase (15 mg) – a Proteolytic Enzyme

Uses and Indications:

Hetrofen SP is prescribed for:

• Rheumatoid arthritis
• Osteoarthritis
• Ankylosing spondylitis
• Postoperative pain
• Musculoskeletal and joint pain

It effectively reduces pain and inflammation associated with these conditions.

Mechanism of Action:

• Aceclofenac inhibits the production of inflammatory cytokines and prostaglandins, reducing inflammation and pain.
• Paracetamol acts centrally to elevate the pain threshold and reduce fever.
• Serratiopeptidase breaks down abnormal proteins at the site of inflammation, aiding in tissue repair and reducing swelling.

Dosage and Administration:

• Take the tablet with food or milk to minimize stomach upset.
• Swallow the tablet whole; do not chew or crush.
• Follow the dosage and duration prescribed by your doctor.

Side Effects:

Common side effects may include:

• Nausea and vomiting
• Stomach pain and indigestion
• Heartburn
• Dizziness and drowsiness
• Diarrhea

Long-term use may lead to serious complications such as stomach bleeding and kidney problems.

Contraindications:

Hetrofen SP should not be used if you have:

• Hypersensitivity to any component of the tablet
• Moderate to severe renal or hepatic impairment
• Severe heart failure
• Pregnancy (especially in the third trimester)

Drug Interactions:

• Paracetamol: May interact with alcohol, barbiturates, carbamazepine, hydantoins, isoniazid, rifampin, and sulfinpyrazone, increasing the risk of liver damage.
• Aceclofenac: May increase plasma concentrations of lithium and digoxin, enhance the activity of anticoagulants, and increase plasma methotrexate levels leading to toxicity if administered within 2–4 hours of methotrexate administration. It may also increase nephrotoxicity when used with diuretics and should be used cautiously with potassium-sparing diuretics.

For Use of Registered Medical Practitioner or A Hospital Only

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