• RHEUMATOID ARTHRITIS
• OSTEOARTHRITIS
• LOW BACK PAIN
• ANKYLOSING SPONDYLITIS
• GOUT
• ACUTE MUSCULO SKELETAL DISORDERS
• PERIARTHRITIS {FROZEN SHOULDER}
• TENOSYNOVITIS
• BURSITIS
• DISLOCATIONS
• PAINFUL POST OPERATIVE CONDITIONS
• PAINFUL INFLAMMATORY CONDITIONS IN GYNAECOLOGY

• HYPERSENSITIVITY
• ACTIVE PEPTIC ULCER
• TREATMENT OF PERIOPERATIVE PAIN IN CABG SURGERY

• INCREASE BLOOD LEVELS OF LITHIUM & DIGOXIN
• INHIBITS DIURETICS
• NOT TO BE GIVEN IV TO PATIENTS WHO ARE RECEIVING OTHER NSAIDS OR ANTICOAGULANTS INCLUDING LOW DOSE HEPARIN.
• INCREASED RISK OF GI ULCERATION AND BLEEDING WHEN USED WITH CORTICOSTEROIDS, ASPIRIN OR ANTICOAGULANTS.
• RENAL FUNCTION MAY BE WORSENED WHEN USED WITH CICLOSPORIN OR TRIAMTERENE.
• ALTERED ABSORPTION WHEN GIVEN WITH SUCRALFATE, COLESTYRAMINE OR COLESTIPOL.

• EPIGASTRIC PAIN
• NAUSEA
• DIARRHOEA
• TIREDNESS
• INSOMNIA
• SKIN RASH
• ITCHING
• GI DISTURBANCES
• HEADACHE
• DIZZINESS
• GI BLEEDING
• PEPTIC ULCERATION
• ABNORMALITIES OF KIDNEY FUNCTION
• LOCAL IRRITATION (RECTAL)

DICLOFENAC HAS POTENT ANTI-INFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIONS. IT INHIBITS THE ENZYME, CYCLOOXYGENASE, THUS RESULTING IN REDUCED SYNTHESIS OF PROSTAGLANDIN PRECURSORS. ABSORPTION: RAPIDLY ABSORBED (ORAL SOLUTION, RECTAL SUPPOSITORY, IM); MORE SLOWLY (ENTERIC-COATED TAB). DISTRIBUTION: PENETRATES SYNOVIAL FLUID; ENTERS BREAST MILK (SMALL AMOUNTS). PROTEIN-BINDING: >99%. METABOLISM: EXTENSIVELY HEPATIC; CONVERTED TO METABOLITES. EXCRETION: ABOUT 60% EXCRETED IN URINE AS GLUCURONIDE AND SULFATE CONJUGATES; 35% IN BILE; 1-2 HR (ELIMINATION HALF-LIFE).

HISTORY OF GI ULCERATION; IMPAIRED CARDIAC, RENAL OR HEPATIC FUNCTION; HYPERTENSION; LACTATION. IV ADMIN IN PATIENTS WITH MODERATE OR SEVERE RENAL IMPAIRMENT; HYPOVOLAEMIA OR DEHYDRATION; ASTHMA, PORPHYRIA. MONITOR LFTS IN PATIENTS ON PROLONGED THERAPY. MAY PROLONG BLEEDING TIME; CAUTION WHEN USED IN PATIENTS WITH COAGULATION DISORDERS OR ON ANTICOAGULANTS. PROLONGED THERAPY MAY INCREASE RISK OF ANAEMIA. 1ST AND 2ND TRIMESTER OF PREGNANCY. ELDERLY, DEBILITATED PATIENTS.

PACKAGING:

1 ML AQ INJECTION (PAINLESS FORMULA) BLISTER PACK BOX WITH 10*5 INJECTION.